Pharmacokinetics and Pharmacodynamics: Second Edition

Author: Wei Shuli, Zhang Qiang
Publisher:
Publish Date: 2004-09-01
Features: Pharmacokinetics and biopharmaceutics are not only of great significance to the research and development of new drugs, new dosage forms, and new preparations, as well as clinical pharmacy, but are also closely related to pharmaceutical sciences, pharmacology, and clinical pharmacology. This book is divided into four parts. The first part discusses the main contents of pharmacokinetics. The second part elaborates on the fundamental principles and basic concepts of pharmacokinetics, providing detailed introductions to various pharmacokinetic models, parameter calculation methods, and blood concentration measurement techniques. It particularly discusses the application of pharmacokinetics and biopharmaceutics in new drug development and research, the development of sustained-release and controlled-release formulations, therapeutic drug monitoring, rational clinical drug use, and experimental studies of certain drugs. The third part covers pharmacokinetic experiments. The fourth part is a solutions section, collecting 244 exercises, including conceptual questions and calculation problems, as well as graphical methods and linear regression methods, with accompanying computer programs. This book combines theory with practice, offering comprehensive coverage of principles, experiments, and solutions, while also reflecting some recent developments in pharmacokinetics, such as population pharmacokinetics. The content is rich and can serve as a textbook for medical and pharmaceutical schools, as well as a reference for research units in drug and drug formulation, pharmacologists, hospital pharmacists, physicians, clinical laboratory scientists, and pharmaceutical industry technicians.