Jinan Wanhou Infertility Hospital

Patient's question:

What treatment is best for azoospermia and when is the best time to treat it? April 10th

Doctor's answer:

Hello: Azoospermia is divided into two major categories. The first category is testicular spermatogenic dysfunction, where sperm cannot be produced, also known as true azoospermia. The second category is normal testicular spermatogenic function, but with obstructed spermatic ducts, preventing sperm from being expelled from the body, known as obstructive azoospermia. For obstructive azoospermia, our hospital adopts the microsurgical precise localization of vas deferens full-layer anastomosis technique, which can achieve a reconnection rate of over 80% in the spermatic ducts.
True azoospermia is not absolutely untreatable, as its causes or etiologies mainly include genetic diseases, congenital testicular abnormalities, testicular lesions, endocrine diseases, severe systemic diseases, malnutrition, radiation damage, and drug effects. Therefore, it is essential to identify the specific cause or etiology of true azoospermia and treat it accordingly. For radiation-induced azoospermia, it is necessary to avoid exposure to radiation sources. For drug-induced azoospermia, the drug should be discontinued or replaced with another. However, the treatment of true azoospermia caused by sperm production dysfunction is often less effective, especially in cases of orchidectomy or severe testicular pathological changes. Identifying the cause of azoospermia is crucial, as some forms of azoospermia can be treated or addressed through assisted reproductive technologies to help individuals have their own children.
Wishing you good health.

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