Patient's question:
A month ago, my son was diagnosed with nephrotic syndrome and then developed edema in all four limbs. At first, I thought his weight had decreased, but later problems arose, and the situation worsened. One of his hands was pressed so hard that he now has to rely on traditional Chinese medicine for treatment, but his condition remains unstable.Doctor's answer:
Nephrotic syndrome in children should first identify the cause. Common causes include: first, familial genetic diseases; second, congenital nephrotic syndrome; and third, primary glomerular diseases. Excluding the first two causes, primary glomerular diseases should be considered first. Primary glomerular diseases in children leading to nephrotic syndrome are mostly of the minimal change type pathologically. Clinically, they present as simple massive proteinuria without hematuria and can be diagnosed based on clinical symptoms and signs. Treatment primarily involves the use of glucocorticoids to suppress immune and inflammatory responses. Minimal change nephrotic syndrome is relatively sensitive to glucocorticoid treatment, with good outcomes, and most patients can achieve negative urine protein within one month.