What are the main reasons for high transaminase levels in fatty liver?

Patient's question:

My husband went to the hospital for a thorough check-up because he always feels tired and dizzy, and sometimes nausea. The results of the detailed examination showed moderate fatty liver, and his ALT level was also high, at 150. Is his condition very serious? Is the liver damage severe? Is his disease not just simple fatty liver? I am very worried now.

Doctor's answer:

High levels of transaminase indicate not only fatty liver but also possible inflammation in liver cells. If liver cells are inflamed, we need to implement liver-protecting and anti-inflammatory treatment. If left untreated, the liver will gradually redevelop inflammation, pus formation, and fibrosis. If fatty liver recurs with liver inflammation, medication intervention is essential.
Some causes of fatty liver include:
Cause #1: Long-term alcohol abuse. Alcohol is the second assassin harming the liver.
Cause #2: Nutritional excess, where nutrients exceeding the body's needs are stored as fat, leading to obesity, high blood lipids, and fatty liver.

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