Epigenetics - Principles, Techniques, and Practice

Author: Xue Jinglun
Publisher:
Publish Date: 2006-12-01
Features: This book primarily elaborates on the basic concepts, historical development, epigenetic phenomena, and their molecular mechanisms of epigenetics, while also providing a comprehensive and systematic introduction to the applications of epigenetics in biomedical fields and the commonly used techniques in epigenetic research. The book is divided into 22 chapters, mainly covering chromatin structure and function, gene expression regulation in eukaryotic cells, epigenetic phenomena, DNA methylation, histone modifications, chromatin remodeling, chromatin compartmentalization, insulator and gene cluster regulation, siRNA and miRNA-mediated regulation, nuclear matrix molecules in gene expression regulation, epigenetic regulation during disease formation, epigenetics of cancer, epigenetic regulation in the immune system, epigenetics in individual development, epigenetics and evolution, epigenetics and aging, epigenetics of cell differentiation, epigenetics and stem cells, epigenetics and the environment, epigenetic therapy and gene therapy, plant epigenetics, and epigenetic research techniques. This book can serve as an introductory reference for researchers in life sciences studying epigenetics, as well as a textbook for graduate students in genetics at universities.