Can men with nonliquefying sperm still have children?

Patient's question:

Hello, I want to ask if it's still possible to have children if the sperm does not liquefy. In the past three months, my wife and I have had sex without using a condom, but she hasn't been able to get pregnant. I used to have the habit of masturbation and it was quite frequent. Now, the duration of my sexual activity is not long, and the sperm is in a jelly-like state—is this due to not liquefying? Can sperm that does not liquefy still lead to fertility?

Doctor's answer:

Hello: Regarding the question of whether infertility can occur due to semen not liquefying, semen liquefaction failure is caused by a lack of secretion or damage of proteolytic enzymes, leading to the loss of control of the enzyme system. This results in some patients' semen remaining non-liquefied for extended periods or liquefying incompletely, with excessively high viscosity. Semen not liquefying often appears as clumpy sperm, similar to the jelly we commonly use. Once this condition occurs, it should be taken seriously. Generally, this situation does not resolve on its own. Doctors indicate that this condition is commonly associated with prostatitis and seminal vesiculitis. The above is the answer to whether infertility can occur due to semen not liquefying, and it is hoped that it will be helpful to you.

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