Patient's question:
Go for an amniocentesis, will Down syndrome be cured? The result is 1:150.Doctor's answer:
Analysis of the Condition: Hello, whether you choose to proceed is up to you, but it's important to understand these points first. The Down syndrome screening is a preliminary test: the high-risk group indicates a higher likelihood of the fetus being a Down syndrome child, while there is still a possibility in the low-risk group. A blood screening value greater than 1/270 classifies a person as high-risk, with a normal value around 1/700. The international standard is 1/270. Additionally, the Down syndrome screening value is a corrected value. The main factors affecting the Down syndrome screening value include: the mother's age, gestational age, the fetal alpha-fetoprotein (AFP) secreted by the fetus, human chorionic gonadotropin (hCG) secreted by the placenta, drug factors, and genetic factors, among others. Taking "Dolima" for fetal preservation may cause hCG to exceed the normal value, potentially affecting the Down syndrome screening result.Recommendation: Currently, the only medical method to determine if the fetus is a Down syndrome child is through amniocentesis. Amniocentesis involves extracting amniotic fluid, culturing fetal cells that have fallen into the fluid, and examining the chromosomes of the cells (specifically the 21st chromosome of the fetus).
Amniotic fluid extraction: 20ml of amniotic fluid is collected, with risks including potential infection, amniotic fluid leakage, and miscarriage. The probability of miscarriage is 1/1000.