Patient's question:
Female, 36 years old, with one child. Since 2014, she has experienced abnormal leukorrhea, which is white and. After a thorough examination at the hospital, it was diagnosed as trichomoniasis vaginitis. In 2017, during a unit health check, a TCT test revealed moderate cervical inflammation, and an HPV test was positive for high-risk type 16. The prenatal doctor prescribed anti-HPV interferon, and she took a total of 10 boxes over a 20-day course. Two months after stopping the medication, a follow-up TCT test showed severe inflammation, with an HPV detection value of 5413.87. A biopsy revealed chronic cervical inflammation with papillary dysplasia, with some areas classified as CN1. The doctor recommended a LEEP surgery. Additionally, she consulted another doctor, who suggested a temporary rigorous treatment approach. Currently, she is using Baofukang and interferon, alternating every other day. As of today, she has been using the medication for 27 days, and her leukorrhea has returned to normal. She wants to consult the doctor about her condition.Doctor's answer:
In fact, there is currently no evidence to prove that the recurrence of cervical lesions is related to the level of HPV values. For acute HPV infection, it can be imagined that the obtained values will be very high. From the perspective of the disease recurrence mechanism, whether it will become cancerous depends on how the virus integrates into key sites of the cell DNA, as well as the level of the cells that have been integrated. So, this is actually a pure probability issue, and also a matter of all or nothing—either it integrates into key sites.