Biopharmaceutical equipment and separation and purification technology

Author: Li Jin
Publisher:
Publish Date: 2003-06-01
Features: The target readers of this book are research and technical personnel, management personnel, and faculty and students of pharmacy in biotechnology pharmaceutical enterprises and universities. The book consists of three parts: Public Utilities and Equipment, Separation and Purification Technology and Application. The first part introduces the principles, structures, functions, applications, and validation techniques of general clean room air environment purification and regulation, automatic control and monitoring, and key production line and process service systems in biopharmaceutical production. The second part focuses on mainstream technologies used in the separation and purification of important biotechnological drug components, including cell disruption, salting out, centrifugation and ultracentrifugation, chromatography, filtration and ultrafiltration, extraction, and freeze-drying technology. It also introduces the validation principles of these technologies and related equipment. The third part takes representative modern biopharmaceutical products as examples to briefly introduce the applications of various separation and purification technologies in the production processes of vaccines, blood preparations, cytokines, enzymes, peptides, traditional Chinese medicine components, and their quality control key points. This book combines basic principles and primarily introduces biopharmaceutical equipment and separation and purification-related technologies, serving as a practical technical reference for the biotechnology pharmaceutical industry. It comprehensively summarizes related technologies, experiences, achievements, and developments.