Patient's question:
Female, 3 years and 5 months. After a long-distance trip home during the Spring Festival, she has been crying at night. On March 13, it was discovered that she had ptosis of the upper eyelid of her left eye and visited the hospital for eye problems, but no issues were found. On March 17, during a trial visit to the kindergarten, it was found that she had no hepatitis B antibodies. On March 19, she received the hepatitis B vaccine (left arm), after which she constantly complained of pain in the left arm and the small finger of her left hand, which was relieved after being pinched. On March 30, a small lump was observed on the left side of her neck. At that time, ultrasound showed ( small nodules in a string-like arrangement), and it was recommended to transfer to a secondary hospital for further treatment. On March 31, after an MRI examination, the diagnosis was a space-occupying lesion in the left neck and posterior upper mediastinum, with a high possibility of a neurogenic tumor (neuroblastoma not ruled out). Left pleural effusion.Doctor's answer:
The only way to confirm the diagnosis is through bone marrow aspiration or biopsy pathology. Pathological diagnosis is the most definitive diagnosis. 24-hour urine VMA and blood NSE can help with diagnosis. The prognosis for mediastinal neuroblastoma is relatively good! Most tumors can be surgically resected. At our Shanghai Children's Medical Center, we have the best hematology-oncology and oncologic surgery departments in the country. We diagnose and treat over 60 cases of neuroblastoma annually, while its incidence rate is only 1 in 100,000.