Will kidney problems be inherited for several generations?

Patient's question:

My grandmother has kidney problems. She didn't get sick until she gave birth to my father. Later, she got sick and gave birth to my aunt and uncle. Now, both my aunt and uncle have kidney problems, but my father hasn't shown any issues with this so far. I'm also over 30 and haven't noticed any problems. My son is now 4 years old, and so far, no issues have been detected. I wonder if my son will develop this problem in the future?

Doctor's answer:

Hello! Your situation involves a familial history of kidney disease genetics. This indicates a genetic predisposition, meaning you have a higher risk of developing kidney disease in the future, but it does not guarantee that you will definitely get kidney disease.
Advice: Since your father does not have this issue, it suggests his genetic predisposition is already low. Therefore, the likelihood of you and your son developing kidney disease in the future is relatively small. However, because someone in your family has this condition, compared to the general population, members of your family may be more prone to it. Thus, it is important to pay attention to kidney protection in daily life. Maintain a regular lifestyle.
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