Patient's question:
Can a woman with an abnormality in chromosome 21 still have children? Is there a relationship between the two miscarriages and the chromosome?Doctor's answer:
Analysis of the condition:If the mother has a D/G translocation, there is a 10% risk for each pregnancy. If the mother is a 21q/21q translocation carrier, her offspring have a 100% risk of developing this condition. There is a certain relationship between miscarriage.
Suggestions:
Normal somatic cells have 46 chromosomes with specific morphology and structure. Abnormalities in the morphology, structure, or number of chromosomes are referred to as chromosomal abnormalities. Diseases caused by chromosomal abnormalities are called chromosomal diseases. Over 100 types of chromosomal diseases have been identified. Chromosomal diseases can clinically lead to miscarriage, Down syndrome, and congenital multiple malformations.