How to further examine high risk of Down syndrome

Patient's question:

21 trisomy high risk, what are some good solutions? Please suggest some methods that do not harm the baby's safety. Thank you

Doctor's answer:

Hello, if the Down syndrome screening shows a high risk of trisomy 21, then you need to have a further amniocentesis for chromosomal abnormality testing. If the trisomy 21 is high risk, then an amniocentesis needs to be performed for chromosomal abnormality testing to rule out the possibility of chromosomal abnormalities in the child.