What is the success rate of IVF for couples with chromosomal abnormalities?

Patient's question:

Female, detected with CA125 value of 46.58, received one injection of leuprolide acetate.
Female karyotype result: 46, XX, 16qh+.
Male karyotype result: 46, X, Yqh+.
Both partners have chromosomal issues. Can the culture dish be successful? What is the chance? Will the child be healthy? Are there successful cases?

Doctor's answer:

It is recommended to undergo third-generation in vitro fertilization, which involves taking genetic material from the embryo before implantation to perform predictions and confirm any abnormalities, thereby selecting healthy embryos for implantation to prevent the transmission of genetic diseases.
2. The success rate of third-generation in vitro fertilization fluctuates between 30% and 70%, depending on the region and hospital.
3. Since all embryos undergo selection before implantation, the born infants are healthy.

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