What are the causes of chromosome 6 abnormalities?

Patient's question:

My friend's wife is nearly 28 years old. She has had three or four miscarriages in a year, all due to fetal arrest. The hospital said it's because of a 16 chromosome abnormality. Could you please tell me the cause of this abnormality?

Doctor's answer:

The reasons for abnormalities in chromosome 6 are very complex. For example, if chromosomes are exposed to radiation for a long time, it may lead to chromosome damage, changes in chromosome position, and abnormal chromosomes, which can result in abnormalities in chromosome 16. For instance, contact with various chemicals in daily life may enter the human body through various pathways, leading to chromosome aberrations. Chromosomes contain genes. If chromosomes are abnormal, it may cause abnormal gene expression. Genes regulate the differentiation of human cells and the production of various proteins in the body. Once genes are abnormal, the consequences are unimaginable. People often hear about abnormalities in chromosome 16. The reasons for these abnormalities are very complex.

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