Patient's question:
I have been married to my husband for over three years, and we are planning to have a child recently. During a conversation with my mother-in-law, I accidentally overheard her say that my husband's parents were first cousins. However, everything about my husband is normal, and he has no health problems. I searched online and found that some people say inbreeding can lead to genetic inheritance across generations. Now, I'm too scared to have a child.Doctor's answer:
Hello, consanguineous marriage increases the risk of developing recessive genetic diseases, such as albinism, congenital deafness and mute; cerebellar malformation, phenylketonuria, galactosemia, etc.; it can also increase the incidence of polygenic genetic diseases, common ones include hydrocephalus, spina bifida, anencephaly, schizophrenia, congenital heart disease, epilepsy, etc.