Principles and Methods of New Drug Design

Author: Xu Wenfang
Publisher:
Publish Date: 2000-01-01
Features: Introduction This book is divided into two parts in terms of content. The first five chapters focus on introducing the molecular biology and molecular pharmacology foundations of drug action, elaborating on the structure, function, and interactions between drug-target biomolecules—proteins and nucleic acids—and drugs. Additionally, the receptors in the body that drugs act upon are not present solely for exogenous drugs. The body always has corresponding small-molecule bioactive substances as ligands. Exogenous drugs, whether intentionally or unintentionally, directly or indirectly, simulate these endogenous active substances to exert pharmacological regulatory effects on the body.