Pharmacokinetics of Antimicrobial Drugs: Principles, Methods, Applications

Author: Qiumule (Germany)
Publisher:
Publish Date: 1999-02-01
Features: Introduction, Content Summary
Pharmacokinetic and pharmacodynamic studies of antimicrobial drugs have become an important component of clinical pharmacology and clinical pharmacy. They provide a basis for determining rational treatment regimens and scientifically evaluating clinical efficacy. Based on the exposition of pharmacokinetic theories, models, and efficacy evaluation methods, the author summarizes the physicochemical properties, mechanisms of action, pharmacokinetic profiles under normal and pathological conditions, and their clinical significance of various commonly used antimicrobial drugs in clinical practice. The author also conducts an in-depth exploration of species differences in pharmacokinetics and animal models, introducing fundamental methods for interpreting preclinical pharmacokinetic and toxicological results through interspecies scaling techniques. This book is systematic and scientifically rigorous, reflecting the latest research findings and development trends in this field, and holds high clinical utility. It can serve as a reference for clinical pharmacists, researchers, and clinicians in the fields of pharmacy, clinical medicine, clinical pharmacology, and biomedical sciences, as well as for faculty and students at higher education institutions.