Patient's question:
I am 38 years old. Recently, I feel that my liver is very tired. I haven't had much appetite, and at night, I always feel a sharp pain in my stomach. I went to a nearby hospital for a check-up and was told it was liver disease. They asked me to get an injection. Is it a good thing if the hepatitis B surface antigen (HBeAg) turns from positive () to negative ()?Doctor's answer:
A turning into a big two positive may indicate a worsening of the condition. If it transforms into a big two positive, it often suggests that the disease is expanding further. It is recommended to improve liver function tests, conduct a thorough liver ultrasound examination, and receive further treatment. A big two positive is usually more dangerous than a big three positive. Of course, it could also be a transitional phase where the disease is improving, especially if accompanied by an increase in hepatitis B DNA quantification.