What should be noted when performing ABO blood group incompatibility tests?

Patient's question:

During pregnancy, my friend told me that routine blood type testing is necessary before delivery. She suggested I undergo an ABO hemolysis first screening test because it's my first pregnancy. Since I have no experience, I was wondering if this screening test is necessary? What should I pay attention to during the ABO hemolysis first screening test?

Doctor's answer:

ABO hemolysis refers to the antigen-antibody reaction caused by blood type incompatibility. Neonatal ABO hemolytic disease is relatively common in clinical diagnosis, often occurring when the mother is type O blood and the fetus is type A or B blood. During early pregnancy, fetal red blood cells enter the mother's body, leading to the production of anti-A or anti-B antibodies in the mother. During delivery, these antibodies may enter the fetus, causing the disease. This condition is very dangerous, so it is essential to undergo this test carefully during pregnancy.

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