What causes Kawasaki disease?

Patient's question:

My child has been having frequent colds and fever recently, and has also developed purple lips and a rash all over the body. After a thorough examination at the hospital, it was diagnosed as Kawasaki disease. So, I would like to consult about what causes Kawasaki disease.

Doctor's answer:

Kawasaki disease is also known as mucocutaneous lymph node syndrome. The cause remains unclear, and most people now believe it is related to viral infection. Infants and children may develop Kawasaki disease. The main symptoms include persistent fever lasting more than 5-11 days, with temperatures often exceeding 39°C, and ineffective treatment with antibiotics. Bilateral conjunctival congestion, red and cracked lips, a strawberry-like tongue, hardened and swollen hands, early redness of the palms and soles, and typical large patches of peeling on the fingertips after 10 days. Most swelling occurs on one side with mild tenderness. It typically reappears within 3 days after fever and recovers within a few days. Shortly after the fever (about 1-4 days), maculopapular rashes or polymorphic erythema may reappear, and occasionally heat rash may develop, primarily on the trunk, but without blisters or crusts.

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