How should Kawasaki disease be diagnosed?

Patient's question:

The child in your aunt's family has just turned five years old, but I often hear your aunt say that her brother frequently has hot skin, rashes, non-purulent lymph node enlargement in the neck. Friends who are unfamiliar with this situation said that her brother might be suffering from Kawasaki disease. So, how is Kawasaki disease diagnosed?

Doctor's answer:

Due to the atypical clinical manifestations of incomplete Kawasaki disease (IKD) and the lack of specific laboratory diagnostic markers, the misdiagnosis rate is very high. It is often misdiagnosed as a cold, sepsis, drug allergy, scarlet fever, measles, adenovirus infection, etc. In particular, it is more likely to be mistaken for a common cold or sepsis, leading to missed opportunities for optimal treatment. Compared to typical Kawasaki disease, it is more likely to cause coronary artery damage and a poorer prognosis.

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