Will motor neuron disease lead to weight gain?

Patient's question:

I went to the hospital for a thorough examination, and the doctor said I have motor neuron disease. I want to know if motor neuron disease can cause weight gain? What are the reasons for this weight gain? Is there any way to treat motor neuron disease?

Doctor's answer:

Motor neuron disease (MND) is a group of chronic progressive neurodegenerative diseases with an unknown cause, which selectively attacks anterior horn cells of the spinal cord, motor neurons in the brainstem, cortical pyramidal cells, and the pyramidal tract. The incidence rate is approximately 1-3 per 100,000 per year, and the prevalence rate is 4-8 per 100,000 per year. The cause of MND remains unclear. It is generally believed that this is due to genetically susceptible individuals exposed to unfavorable age-related environmental factors, meaning that both genetic and environmental factors contribute to motor neuron disease.

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