Patient's question:
I had an outbreak of illness in October 2009, triggered by a cold. Treatment began in February 2010. The kidney biopsy pathology showed Henoch-Sch?nlein purpura nephritis (ISKD classification—IIIb). I was taking Eculizumab and hormones, but the medication has now been discontinued. However, the protein and hematuria levels remain at 2, with no decrease. Only the purpura has disappeared. Now, how should I be treated, and what kind of help do I need: Can the protein and hematuria levels still be reduced?Doctor's answer:
Hemolytic nephritis is self-limiting in most pediatric patients, with symptoms naturally resolving within several months. However, adult patients have a poorer prognosis, with only 50% achieving complete natural recovery. If a clear sepsis factor is identified, it should be prevented as much as possible. General antihistamines such as diphenhydramine and chlorpheniramine maleate tablets can be taken orally. Prophylactic antibiotics (e.g., penicillin) should be avoided as much as possible. For joint symptoms, aminopyrine can be used, while aspirin is generally preferred. If other manifestations of kidney disease, such as edema or hypertension, are present, the management should be the same as for chronic nephritis.