Patient's question:
I was diagnosed with hepatitis B in 2007, and at that time, my hepatitis B virus DNA was 10^8. My liver function was abnormal, and it remained so until the first half of 2009. In the second half of 2009, my liver function returned to normal. In December 2009, my DNA virus test result was 3.14 10^3, and my hepatitis B serology was positive for anti-HBs and HBeAg (so-called "minor double-positive"). Last week, I had a full set of tests again. My hepatitis B serology was still positive for anti-HBs and HBeAg, my DNA virus level was above the detection limit, but my liver function was normal (AST 19, ALT 16, AST/ALT ratio 1.2, which is slightly elevated).What kind of help I need: Could you please help me speculate whether my condition is improving or worsening? Is there a possibility of complete seroconversion in my case? Can someone like me get pregnant? What precautions should I take?
Doctor's answer:
I don't know if your condition has been treated. Based on the liver function and hepatitis B five-item test results, the disease is expanding in a positive direction. In this case, you have a hepatitis B infectious status, so you need to pay attention to your diet and rest, and have irregular follow-up tests. After contracting hepatitis B, it is impossible for all indicators to turn negative. Treatment can be considered successful as long as one item turns negative, in other words, a 2.5 positive result is the standard for full recovery. In your current condition, it is best to rest for a period of time before getting pregnant, as pregnancy can easily relieve liver pressure and trigger repeated episodes of the disease.