Patient's question:
The director of our factory was initially diagnosed with minor hepatitis B, which later worsened into major hepatitis B. Due to work-related reasons, he had to continuously smoke and drink beer. Now, he has developed fatty liver and has been experiencing persistent fever and cough, with low-grade fever that won't subside. His eyes and skin have also become yellow.Doctor's answer:
Liver cirrhosis is more severe. For HBeAg-negative chronic hepatitis B patients with liver cirrhosis (60% of them), treated with PegIFNα-2a for 48 weeks, 43% of patients had HBV-DNA <10^4 copies/mL (equivalent to 2000 IU/mL) during 24 weeks of follow-up after stopping the medication, and 42% during 48 weeks of follow-up. The rate of HBsAg loss was 3% during 24 weeks of follow-up after stopping the medication, and increased to 8% after 3 years of follow-up. The daily treatment for patients with liver cirrhosis is mainly symptomatic treatment. Patients can take many oral medications, coordinate with various vitamins, and pay attention to regular routines, while avoiding smoking and alcohol.