Is interferon treatment effective for chronic hepatitis B with high viral load?

Patient's question:

Doctor, my husband has been diagnosed with chronic hepatitis B. Because taking medication can affect having children in the future, if he undergoes interferon treatment under anesthesia, what adverse reactions might the body have? Also, how long should the anesthesia time be for the treatment, which is administered once a week, because I cannot take too much time off work?

Doctor's answer:

Your husband has been diagnosed with chronic hepatitis B (). If his liver function tests are normal, it means he is a hepatitis B virus carrier, and the hepatitis B virus is in a "peaceful coexistence" state with his body. The harm caused by the hepatitis B virus copies can be compensated by the liver. In China, 10% of the population is similar to him and does not require special treatment, just normal management. It is best not to share eating utensils, towels, etc. with family members.
If considering interferon antiviral treatment, it generally needs to be taken for more than a year. In the initial stages of treatment, side effects such as fever and an increase in white blood cells may occur. It is recommended that your husband pay attention to rest, eat more fresh vegetables and fruits, reduce the intake of greasy and spicy foods, quit smoking and drinking, and undergo periodic liver function tests, ultrasound of the liver, gallbladder, pancreas, and spleen, as well as AFP tests. If any issues arise, he should seek follow-up treatment promptly.

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