What are the clinical stages of nephrotic syndrome?

Patient's question:

I would like to ask a friend who has kidney disease graded 4, what are the clinical stages of this severe nephrotic syndrome? Please let me know if you know.

Doctor's answer:

What you mentioned as the fifth main type refers to mesangial fibrosis nephropathy. Its treatment is primarily based on hormone and immunosuppressive therapy. It is more common in young people and has a better prognosis. The main clinical manifestations of severe nephrotic syndrome include hypoproteinemia, severe edema, large amounts of proteinuria, and hyperlipidemia. Its pathological classification is mainly divided into five types: minimal change nephritis, membranous nephritis, mesangial fibrosis nephropathy, membranofibrosis nephropathy, and focal segmental glomerulosclerosis.

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