What is the reason why semen does not liquefy?

Patient's question:

I've been divorced for two years and haven't had any children yet. A few days ago, I went to the hospital and the doctor said I have a condition where semen doesn't liquefy, which is why I can't conceive.

Doctor's answer:

Hello: Semen liquefaction failure is caused by a lack of excretion or destruction of proteolytic enzymes, leading to endocrine disorders in the enzyme system. This results in many patients' semen remaining unliquefied after being placed for 1 hour, or liquefying incompletely with excessively high viscosity. In such cases, sperm cannot move, naturally leading to infertility. This condition is often associated with infections in accessory glands that disrupt the excretion of proteolytic enzymes, fibrinolytic enzymes, and semen liquefying factors, making it impossible for semen to liquefy. It is recommended that you visit the hospital early for a thorough examination to identify the underlying cause and receive targeted treatment to avoid interfering with conception. Wishing you good health!

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