Absorption, Distribution, Metabolism, Excretion, Toxicity and Efficacy of Traditional Chinese Medicine Components - (Volume 2)

Author: Yang Xiuli
Publisher:
Publish Date: 2006-08-01
Features: This book is divided into two volumes and explores the various mechanisms and theories of the absorption, distribution, metabolism, excretion, toxicity, and pharmacological effects (ADME/tox.act.) of traditional Chinese medicines (TCMs). It investigates the influence of various dosage form factors and biological factors on pharmacological effects, providing rigorous evaluation criteria for controlling the intrinsic quality of drug formulations, ensuring the safety and efficacy of final products, and supporting new drug development and clinical applications. This book holds significant theoretical and practical importance. Given the complexity of TCMs, pharmacokinetic studies of TCMs using active or toxic components as indicators, as well as studies using pharmacological or toxicological effects as indicators, play a crucial role in inheriting traditional Chinese medicine theory, modernizing the study of TCMs, and advancing the modernization of TCMs. This book summarizes research findings on the absorption, distribution, metabolism, excretion, and toxicity (ADME/tox.) of TCM components, as well as related pharmacological effects, and is divided into two parts: the General Introduction and the Specific Topics. The Specific Topics are further divided into eight chapters, organized by the structural types of TCM chemical components, covering 475 TCM components in total, with over 2.8 million words. Each entry for a TCM chemical component includes twelve sections: 【Chemical Name】, 【English Name】, 【Synonyms】, 【Structural Formula】, 【Molecular Formula and Molecular Weight】, 【Source】, 【ADME/tox.】, 【Biological Activity】, 【Analytical Methods】, 【Spectroscopic Data of Chemical Structures】, 【Remarks】, and 【References】. The content is rich, the text and illustrations are detailed, and the scientific rigor makes it a valuable reference for researchers actively engaged in modernizing TCMs, as well as for a broad audience of TCM practitioners, integrated Chinese and Western medicine professionals, and master's and doctoral students in related fields.