How to determine if a testicular biopsy is abnormal?

Patient's question:

How to identify abnormalities in a testicular biopsy? Hello, I am 23 years old, unmarried, and have no children. My wife and I recently want to have a child, so I want to thoroughly examine my body. Therefore, I plan to undergo a testicular biopsy, but I don't know how to interpret the test report. Could you please help me understand it? Thank you! Desired assistance: How to identify abnormalities in a testicular biopsy?

Doctor's answer:

Spermatogenic epithelial desquamation type: Seminiferous tubules are dilated, with most or all lumen filled with desquamated spermatogenic cells, the lumen disappears, often accompanied by changes in the basement membrane and small blood vessels to varying degrees. Spermatogenic arrest or maturation disorder type: The spermatogenesis process is often arrested at the spermatocyte or spermatid stage, often accompanied by changes in spermatocytes, the basement membrane, and blood vessels, which is a mitotic abnormality of the spermatogenesis process. Spermatogenic function torsion type: All levels of spermatogenic cells and sperm uniformly decrease, encouraging cells to reappear with a large number of vacuoles.

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