Vaccine Key Technology Detailed Explanation - (Second Edition of the Original)

Author: (English) Robinson, Hudson, Cranitch (editors), translated by Li Qihan and others
Publisher:
Publishing Date: 2006-09-01
Features: Since the publication of this book, significant advancements have been made in areas related to vaccine research, such as bacterial genomics, quantitative techniques for antigen-specific T cells, gene manipulation techniques for vaccine vectors, the application of natural regulatory molecules in immune responses, and DNA vaccinology. Therefore, the new edition has been specifically expanded to include several new chapters, such as "Live Virus Vaccine Vectors," "Attenuated Bacterial Vaccines," "Immunomodulatory Factors," "MHC-Peptide Tetramer Complexes," and "Identification of Candidate Strains Using Gene Analysis." Additionally, each chapter has been supplemented with new methods that have emerged in the field of vaccinology since the previous edition. This book is structurally complete and consists of the following three aspects: ① Detailed descriptions of the use of specific techniques in vaccine development, including the attenuation of viruses or bacteria using gene manipulation techniques, the preparation of vectors, the inactivation of toxins, and the production of synthetic peptide vaccines and adjuvant vaccines; ② More comprehensive technical descriptions of vaccine formulations and delivery systems, as well as the evaluation of immune responses; ③ In several chapters, comprehensive discussions are also provided on the large-scale production of vaccines, vaccine quality assurance, clinical trials, and other related topics to offer readers relevant background knowledge. In summary, through these comprehensive discussions on vaccine development, this book should provide valuable information for those dedicated to researching and improving or developing new vaccines.