What is the reason for high white blood cell count and low neutrophil count in children?

Patient's question:

What is the reason for high white blood cell count and low neutrophil count in children? Is there a good solution? Can it be treated? Please give advice from a doctor.

Doctor's answer:

If the child shows no abnormalities, a follow-up check in a few days may be recommended. Sometimes there may also be physiological temporary elevations, which should be accompanied by neutrophil elevation. A significant increase in white blood cells is abnormal, while a slight decrease in neutrophils is not meaningful due to potential machine errors. I’m not sure if the absolute value of neutrophils is normal. A follow-up check after taking medication for 3 days could help determine if it returns to normal. Typically, elevated white blood cells are accompanied by elevated neutrophils, and low white blood cells are accompanied by low neutrophils. This is because white blood cells are primarily influenced by neutrophils, and sometimes also by lymphocytes. If white blood cells are high but neutrophils are low, lymphocytes must be elevated. However, you mentioned that other values are normal, which does not align with the expected pattern.

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