Patient's question:
Married for many years without pregnancy, checked and found suffering from semen nonliquefaction, what are the causes of semen nonliquefactionDoctor's answer:
Ejaculate liquefaction failure is caused by a deficiency or destruction of proteolytic enzymes, leading to endocrine dysfunction of the enzyme system. As a result, many patients' semen remains unliquefied after being placed for 1 hour, or liquefies incompletely with excessively high viscosity. In such cases, sperm cannot migrate, naturally leading to infertility. This condition is associated with infections of the accessory glands, which disrupt the secretion of proteolytic enzymes, fibrinolytic enzymes, and semen liquefaction factors, preventing the liquefaction of semen.