Patient's question:
Is it better to undergo bone marrow transplantation or continue chemotherapy for leukemic encephalopathy? Current situation for high-risk L2 acute lymphoblastic leukemia with encephalopathy: good response to chemotherapy so far. Medical history: diagnosed with leukemia in 2005, undergoing regular chemotherapy. Encephalopathy was detected in 2006, followed by two cycles of high-dose chemotherapy, with the condition stabilized.Doctor's answer:
White matter disease is a structural change in the brain characterized by damage to the myelin sheath of central nervous system cells. It is characterized by the involvement of white matter tracts in higher brain functions. Its clinical manifestations range from inattention, headache, memory loss, numbness, amnesia, and personality changes to dementia, coma, and even death. Many diseases can occur in the white matter of the brain. The typical response of white matter to various harmful stimuli is demyelination. It may be a secondary manifestation of neurological diseases, such as infection, poisoning, degeneration, post-traumatic, and post-stroke defects.