Patient's question:
My husband has been diagnosed with semen liquefaction disorder for a long time, and he is very distressed. Could you please ask the doctor, what are the common causes of male semen liquefaction disorder?Doctor's answer:
Ejaculate failure to liquefy is commonly caused by conditions such as seminal vesiculitis and prostatitis, which lead to insufficient secretion of fibrinolytic enzymes from the prostate; deficiencies in trace elements (such as magnesium, zinc, etc.); congenital absence of the prostate; and other factors. It is generally believed that the secretions from the prostate and seminal vesicles contribute to the coagulation and liquefaction processes of semen. The coagulation factor produced by the seminal vesicles causes semen to coagulate, while the liquefaction factors produced by the prostate, such as protease and fibrinolytic enzymes, cause semen to liquefy. Once inflammation occurs in the seminal vesicles or prostate again, it can disrupt the secretion of these factors, leading to an excessive accumulation of coagulation factors or an increase in liquefaction factors, resulting in semen failure to liquefy.