How should the treatment be carried out after the discovery of male infertility?

Patient's question:

I was diagnosed with infertility 2 years ago. My wife has always been by my side through the treatment, but it hasn't shown any improvement. I feel truly guilty inside. I don't want to burden my wife if the treatment doesn't work, but I really can't let go. Please ask: What should be done after discovering male infertility?

Doctor's answer:

The causes of male infertility are due to genetic defects, which are caused by a gene called POLG. This gene plays a decisive role in the reproduction and inheritance of DNA in mitochondria. Sperm from men with a mutated POLG gene have weak motility, are defective and deformed, leading to infertility in direct descendants. How long does it take for male infertility treatment to be effective? For your health, if you suffer from this condition, please seek timely treatment at a regular and professional hospital. The main approach is to conduct targeted examinations based on individual circumstances, and under the guidance of a doctor, receive symptomatic treatment. Wishing you good health.

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