At 17 weeks of pregnancy, I had the T21 screening with a value of 1:269, which is considered high-risk.

Patient's question:

Wife, 31 years old, 90 kilograms, 17 weeks and 3 days pregnant
Down syndrome screening results: Serum marker test results, HCG value: 82,156 MOM: 2.0900
AFP value: 44.09 MOM: 0.7600
Total risk calculation results: Calculated risk value Risk threshold (cut-off value)
T21 1:269 1:270
t18 1:38,461 1:349
OND 0.7600 2.5
Evaluation conclusion: High risk for T21, low risk for T18 and OND
Recommended measures: The risk assessment result for the fetus suffering from Down syndrome is higher than the normal pregnant population cutoff threshold during the second trimester, belonging to a high-risk population. It is recommended to consult an obstetrician or go to a qualified unit for prenatal diagnosis.

Doctor's answer:

Hello, yes, prenatal examination---clinical examinations performed on pregnant women and fetuses during pregnancy. Due to the growth and development of the fetus, a series of adaptive changes occur in the various systems of the pregnant woman's body. If these changes exceed the physiological range or the pregnant woman herself suffers from a certain disease that cannot adapt to the changes of pregnancy, then both the pregnant woman and the fetus may develop pathological conditions.