Patient's question:
Where can uterine fibroids infertility be treated in Wuhan? How do uterine fibroids cause infertility?Doctor's answer:
HelloUterine fibroids are the most common solid benign tumors in the female reproductive system. Uterine fibroids are formed by the proliferation of smooth muscle tissue and are most common in the age group of 30 to 40 years. They can grow as a single nodule or in multiple numbers, with varying sizes. The etiology of uterine fibroids is still unclear, but most believe it is related to excessive estrogen stimulation in the body. The incidence of infertility in patients with uterine fibroids is approximately 22 to 32%, with submucosal fibroids having the highest rate of infertility.
Uterine fibroids can be classified based on their location into subserosal fibroids, intramural uterine fibroids, submucosal fibroids, cervical fibroids, and ligament fibroids, among others. Generally, small or solitary subserosal and intramural uterine fibroids do not affect fertility or pregnancy.
Infertility caused by uterine fibroids can occur in the following situations:
(1) Larger uterine fibroids can deform the uterine cavity, making it difficult for sperm to pass through, as well as for the fertilized egg to implant and for fetal development.
(2) Fibroids growing near the uterine angles can compress the opening of the fallopian tubes, causing blockage. Pressure may affect their patency, or the ovaries may be displaced, widening the distance between the ovaries and the fallopian tubes, thereby hindering the fimbriae's function of picking up eggs.
(4) Fibroids growing in the cervix can compress the cervical canal, obstructing the passage or altering the direction of the cervical opening, making it farther from the seminal pool in the posterior fornix, which is unfavorable for sperm entering the cervical opening.
(5) Submucosal fibroids growing in the uterine cavity are like an intrauterine device placed in the cavity, hindering fertility. The endometrium on the surface of the uterine cavity becomes ischemic, necrotic, and atrophic, which is also unfavorable for the implantation of the fertilized egg.
(6) Uterine fibroids can increase the frequency, amplitude, and duration of uterine contractions beyond the normal baseline, interfering with the implantation of the fertilized egg or causing miscarriage after implantation. When fibroids are accompanied by endometriosis, it indicates ovulatory dysfunction, fibroids causing uterine bleeding, leading to infection, and causing fallopian tube blockage—all of which can result in infertility.