Which endocrine factors are prone to cause habitual abortion in women?

Patient's question:

My friend came because she got angry with her husband and lost a child. I have irregular periods all year round, will it be like this too?

Doctor's answer:

First, hyperprolactinemia: Prolactin inhibits corpus luteum function, shortening the luteal phase and leading to insufficient progesterone. It can also affect the normal local prolactin levels in the uterus, impacting embryo development and causing miscarriage. For patients diagnosed with hyperprolactinemia, bromocriptine and other medications should be used under the guidance of a doctor. For those with significant symptoms, traditional Chinese medicine can be combined for regulation.
Second, luteal phase defect: The corpus luteum in the ovary secretes progesterone. Insufficient progesterone can lead to poor endometrial development, hindering implantation of the fertilized egg and early embryo growth. Before 8 weeks of pregnancy, the primary source of progesterone is the corpus luteum of pregnancy. After 8 weeks, placental trophoblast cells gradually replace the corpus luteum as the main source of progesterone. If progesterone is insufficient before 8 weeks, it may result in miscarriage.
Third, polycystic ovary syndrome (PCOS): Approximately 40% of patients with PCOS experience recurrent spontaneous miscarriage, primarily due to conditions such as hyperprolactinemia, luteal phase defect, low estrogen levels, poor egg quality, and endometrial abnormalities. This condition can be treated, and pregnancy should be attempted only when the issue is resolved.

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