Patient's question:
My neighbor's sister is pregnant, but the recent hospital check-up results showed acute fatty liver during pregnancy. This has greatly affected her pregnancy process. For this reason, I would like to know what are the clinical symptoms and manifestations of acute fatty liver during pregnancy?Doctor's answer:
Hello, the clinical symptoms of acute fatty liver of pregnancy include sudden, persistent nausea, vomiting, and even hematemesis, accompanied by upper abdominal pain. Jaundice appears within one week, often without pruritus, followed by a rapid deepening of jaundice, and then varying degrees of consciousness impairment or coma. Serum bilirubin levels are mildly to moderately elevated. If DIC is present, coffee-ground vomit or fresh blood may be observed, along with hematuria, melena, purpura, bleeding from the gums and injection sites. Additionally, platelet and fibrinogen levels decrease, FDP values rise, and prothrombin time prolongs. Half of the patients experience oliguria, metabolic acidosis, and other early manifestations of renal failure.