Patient's question:
At 28 weeks of maternity leave back in my hometown, I found out that my RPR test was negative, but my TPPA test was positive. However, at 14 weeks, the TP test was negative, and both my husband and I had been tested and found to be normal before pregnancy.Doctor's answer:
RPR is the initial screening test for syphilis, and a positive result does not necessarily indicate syphilis; whereas TPPA is the confirmatory test for syphilis. If it is positive, it suggests that the person has been infected with syphilis or is currently infected with it. Now that the TPPA is negative, it indicates that the positive RPR result is not caused by syphilis. Just in case, you can monitor the TPPA or other confirmatory tests for syphilis. If it remains negative consistently, it proves that there has been no infection with syphilis.