Patient's question:
The day before yesterday, I had three tests for antisperm antibodies, and the IgM test came back positive, while the other two were negative. I searched online, and found that a positive IgM result can lead to infertility, which I don't understand at all. My wife was four months pregnant this year when she fell down the stairs and had a miscarriage through artificial induction. Yesterday marked exactly one month after her surgery. We went for a check-up together, planning to have another child in the future. The antisperm antibody test for her came back negative, while mine showed a positive IgM result. Does this really mean infertility? I only got her pregnant in August, and we didn't use contraception properly—it was an accidental pregnancy, not something we planned to have. Why would my test be positive this time?Doctor's answer:
Hello: The possibility of naturally turning negative is small. You can follow the doctor's guidance to re-examine and confirm if it remains positive, and then seek timely treatment. Antisperm antibodies are a type of immunological infertility. Antisperm antibodies are a complex pathological product, affecting both men and women, and their exact causes or etiologies are not yet fully understood. The sperm and seminal fluid of men are specific antigens for women. Upon contact with blood, they can trigger immune reactions in both men and women, leading to the production of corresponding antibodies that hinder the combination of sperm and eggs, resulting in infertility. For immunological infertility, treatments such as isolation therapy, immunosuppressive therapy, and advanced immunization have shown significant effectiveness. It is recommended that you seek early treatment and do not miss the best age for conception. If you have any related questions, feel free to contact us again. Wishing you good health!