What are the factors or causes of progesterone decrease?

Patient's question:

12.6 Blood test, HCG was 13614 (mIU/ml), progesterone PROG was 142 (mol/l), estradiol E2 was 2384.
12.12 Blood test, HCG was 47888 (mIU/ml), progesterone PROG was 107 (mol/l), estradiol E2 was 2769.
I had a natural miscarriage on 10.13, now there is no abdominal pain, no bleeding symptoms, but there is vomiting. However, progesterone has decreased, will it be a miscarriage?
I had a miscarriage in February 2008 due to no fetal heartbeat.

Doctor's answer:

Pathological reduction of progesterone is primarily seen in luteal dysfunction, functional disorders of the corpus luteum, polycystic ovary syndrome, anovulatory dysfunctional uterine bleeding, severe pregnancy-induced hypertension, placental dysfunction during pregnancy, fetal growth restriction, and stillbirth.
Recommendation: This indicates the fetus. Progesterone has decreased, but previous values were good, so it's not necessarily dangerous now. However, since it has decreased, an injection has been administered. Currently, you may not need to be hospitalized and can rest at home. Monitor for any bleeding.
After five days of the injection, you should test progesterone and HCG together to see the results and draw a conclusion. If a B (BC) is needed, it's best to do it 55 days later (especially if there is no bleeding), as the fetal pole and heartbeat will be clearly visible at that time. Otherwise, it would be pointless. If bleeding occurs, don't worry about it—just follow the doctor's instructions for the B.
Lifestyle Care: If progesterone is low during pregnancy, there is a risk of miscarriage. It is recommended to rest in bed, enhance nutrition, and closely monitor the condition under the guidance of a doctor for pregnancy preservation treatment. Remember to take progesterone-boosting medication as prescribed by your doctor.

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