What are the causes or etiology of azoospermia?

Patient's question:

My wife can't get pregnant and has been blaming me, saying it must be my fault. I just refuse to admit it. We went to the hospital for tests, and after the results came back, I was dumbfounded. I have azoospermia. Oh my god, how could this be the result? What are the factors or causes that lead to azoospermia? Can I still be a father?

Doctor's answer:

Hello! There are no differences between the patient's semen and normal semen; their sexual activity process, sexual pleasure, and ejaculation process are all normal. The only difference is that the semen produced by the testicles contains no sperm, resulting in male infertility. Azoospermia can be divided into two categories: obstructive azoospermia and non-obstructive azoospermia due to testicular spermatogenesis dysfunction. The former is caused by congenital or inflammatory factors leading to obstruction of the vas deferens or epididymis, preventing sperm produced by the testicles from being expelled, but there are viable sperm in the testicular or epididymal tissue. The latter is due to congenital developmental abnormalities, testicular lesions, endocrine diseases, radiation damage, drugs, and other systemic factors that cause the testicles to lose their spermatogenesis function, resulting in azoospermia.
Since each patient has different causes of the disease, symptoms, and varying physical constitutions, the treatment methods also differ. It is recommended to visit a authoritative infertility and sterility specialty hospital for comprehensive examinations. The doctor will provide targeted treatment based on your condition. Wishing you early pregnancy and good health!

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