Patient's question:
For four years after getting married, I couldn't get pregnant. Recently, I went to the hospital for a check-up. After some inquiries, the doctor initially suspected that I have immunological infertility and asked me to undergo a detailed examination. I'm not very familiar with this, and I'd like to learn more about what tests are needed for immunological infertility in advance.Doctor's answer:
Hello!1. Intrauterine cervical mucus function test: This primarily examines the function of cervical mucus, sperm viability, and sperm penetration ability.
2. Reproductive immunology test: The examination includes checking sperm antigens, antisperm antibodies, and anti-endometrial antibodies. If conditions permit, further fluid immunology tests can be conducted.
3. In vitro sperm-cervical mucus contact test: This test determines whether antisperm antibodies are present in cervical mucus. The test is performed during the predicted ovulation period, which is a commonly used examination method.
4. Blood-based antisperm antibody detection: If sperm binds to antibodies, they may be immobilized or even die under the synergistic effect of antibodies. Experts note that this test method has strong specificity and good reproducibility but poor sensitivity and a high rate of false negatives. It is recommended to undergo comprehensive testing at a reputable infertility and subfertility specialist hospital. The doctor will provide targeted treatment based on your condition. Wishing you early pregnancy and good health!