Patient's question:
I've been married for five years, but I still haven't been pregnant. Three years ago, my family was already very anxious. First, my husband went to the hospital for a semen check-up, and everything was normal. Then, I underwent tests, which revealed several issues. My cervical mucus and fallopian tubes were normal, but there was a mass with tenderness on the left ovary, while the right ovary was normal. Additionally, I had chronic pelvic inflammatory disease. The doctor finally diagnosed the infertility issue as being related to the ovaries, specifically ovary-related infertility.Doctor's answer:
(1) Turner syndrome and simple gonadal dysgenesis are chromosomal abnormal diseases that primarily manifest as primary amenorrhea, with elevated gonadotropins and decreased estrogen.(2) Premature ovarian failure and polycystic ovary syndrome: High gonadotropin amenorrhea caused by ovarian dysfunction before the age of 40 is termed premature ovarian failure, accounting for approximately 20% to 28% of primary amenorrhea and 4% to 20% of secondary amenorrhea. Women with primary amenorrhea or secondary amenorrhea before the age of 30 exhibit elevated endogenous gonadotropin levels, normal follicles in the ovaries, but show low responsiveness to high-dose exogenous gonadotropin stimulation.
(3) Polycystic ovary syndrome: It is often characterized by amenorrhea or oligomenorrhea, prolonged anovulation, excessive androgens, and non-cyclical fluctuations in estrogen. It is currently a major factor or cause of anovulatory infertility.