Patient's question:
My wife was recently tested and found to have anti-sperm antibodies and anti-ovarian antibodies in her body. We want to find another hospital to get checked again to see if it's really the case. I'm not sure which hospital in Xuzhou is more authoritative, or if any hospitals nearby would be okay?Doctor's answer:
Antisperm antibodies are a complex pathological product that can affect both men and women. The exact factors or causes have not yet been fully clarified. For men, sperm and seminal fluid are specific antigens for women. Upon contact with blood, they can trigger immune responses in both men and women, leading to the production of corresponding antibodies that hinder the combination of sperm and eggs, resulting in infertility. Based on your wife's condition, it is recommended to seek further diagnosis at a local Level 3 Grade A hospital, as lower-tier hospitals do not typically offer this examination. Women with positive antisperm antibodies often have reproductive system infections such as endometritis, vaginitis, or tubulitis before the onset of the condition. In such cases, lymphatic immunotherapy can be used for treatment.Response to the reply on 2012-11-27 15:29:26:
A woman with positive antisperm antibodies falls under the category of immunological infertility. Simply using condoms for contraception does not eliminate the antibodies in her body. Although a test may show negativity when contraception is discontinued, many women still test positive after resuming sexual activity, as sperm entering the female body triggers an antigen-antibody reaction. Additionally, many women mistakenly believe they have converted to negative and skip follow-up tests after intercourse, leading to many experiencing spontaneous miscarriages after pregnancy.
Therefore, there is no time restriction for men to undergo antisperm antibody testing—it can be done at any time. However, for women, the best time to take an antisperm antibody test is 3–5 days after the end of their menstrual period.