Patient's question:
At the age of 25, when I got married to my husband, we both wanted to have children. Now I'm 29, and I've been trying hard, but it just hasn't worked. We're really puzzled because we believe our bodies are healthy and there shouldn't be any problems. We've also studied what the safe period is and what the risky period is, but I just can't get pregnant. I'm so desperate!Doctor's answer:
Okay, here is the English translation of the provided text, following your instructions:I. Endocrine disorders leading to ovulatory dysfunction can cause infertility. Ovulatory dysfunction is one of the factors leading to female infertility. In addition to causing infertility, ovulatory dysfunction can also lead to symptoms such as menstrual disorders, amenorrhea, hirsutism, and obesity. If ovulation does not occur for a long time, sexual hormone metabolism becomes disordered. The endometrium may undergo excessive hyperplasia without the opposing effect of cyclical progesterone, making it easier to develop endometrial cancer and breast cancer.
II. Endocrine disorders When endocrine disorders occur, they can cause ovulatory dysfunction, amenorrhea, polycystic ovary syndrome (PCOS), hirsutism and virilization, hyperprolactinemia, luteal phase defect, functional uterine bleeding, ovulatory bleeding, ovarian insufficiency, and premature ovarian failure, thereby causing infertility.
III. Luteal phase defect Normally, after the ovary ovulates, the follicle luteinizes to form a corpus luteum and secretes estrogens and progesterone. The secretion level reaches its peak 7-8 days after ovulation. If the secretion of pituitary gonadotropins and estrogen is insufficient, the development and maturation of the follicle will not be complete, which often affects corpus luteum development, leading to luteal phase defect. Luteal phase defect accounts for about 3% to 8% of the causes of infertility.