Patient's question:
When should endocrinology be checked?! During menstruation? Or can it be any time? Are there any special requirements?! Also, if you go to the hospital to check for factors or causes of infertility, what is the best time?! I've been married for over a year and haven't had a good pregnancy yet!Doctor's answer:
Hello, the check is most accurate on the third day of the menstrual period.Six Hormones and Their Normal Values:
1) Follicle-Stimulating Hormone (FSH): Blood FSH concentration is 1.5–10 mIU/mL in the pre-ovulatory phase, 8–20 mIU/mL during ovulation, and 2–10 mIU/mL in the post-ovulatory phase. Generally, 5–40 mIU/mL is considered normal.
2) Luteinizing Hormone (LH): Blood LH concentration is 2–15 mIU/mL in the pre-ovulatory phase, 30–100 mIU/mL during ovulation, and 4–10 mIU/mL in the post-ovulatory phase. If high FSH is combined with high LH, ovarian dysfunction is highly certain, and no further tests are needed. An LH/FSH ratio ≥3 is one of the diagnostic criteria for polycystic ovary syndrome (PCOS).
3) Prolactin (PRL): In non-lactating women, the normal blood PRL level is 0.08–0.92 mol/L. A level above 1.0 mol/L indicates hyperprolactinemia.
4) Estradiol (E2): Blood E2 concentration is 48–521 picomoles per liter in the pre-ovulatory phase, 70–1835 picomoles per liter during ovulation, and 272–793 picomoles per liter in the post-ovulatory phase. Low values are seen in ovarian dysfunction, premature ovarian failure, and Sheehan's syndrome.
5) Progesterone (P): Secreted by the corpus luteum of the ovary, its main function is to promote the transformation of the endometrium from the proliferative phase to the secretory phase. Blood P concentration is 0–4.8 mol/L in the pre-ovulatory phase and 7.6–97.6 mol/L in the post-ovulatory phase. Low blood P in the post-ovulatory phase is seen in luteal insufficiency and ovulatory dysfunctional uterine bleeding.
6) Testosterone (T): The normal blood T level in women is 0.7–3.1 mol/L.
During your test, which falls in the ovulatory phase, both FSH (5.88) and LH (12.13) are slightly low, indicating low estrogen levels and insufficient progesterone and luteal function.